Research Areas

2017 - Today (FCMSCSP, São Paulo, Brazil) - Neurogenesis and Psychiatric disorders

  • Financial Support - Grant Approved by   SPRINT-FAPESP  (Project "Mitochondrial metabolism and its relationship with neurogenesis in an anumal model of Schizophrenia with aging" intitulado “Age-related mitochondrial metabolism and its relationship with neurogenesis in an animal model of Schizophrenia”

 

2017 - Today (FCMSCSP, São Paulo, Brazil) - Autophay and Metabolism in Amyotrophic Lateral Sclerosis.

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  • Brazil Visiting Fellow  – University of Birmingham, UK 2018 - “Autophagy investigatoin in iPSCs-derived neurons  from different neurodegenerative models"

  • Brazil Visiting Fellow  – University of Birmingham, UK 2017 - “Autophagy pathways evaluations as a therapeutic strategy  for rare and more prevalent neurodegenerative disorders"

  • Financial Support - Grant Approved by  FAPESP International Cooperation FAPESP-UoBirmingham-UoNottigham (Project: “Investigating cellular homeostatic mechanisms underlying rare and prevalent neurodegenerative diseases using human induced pluripotent stem cells”

  • Financial Support - Grant Approved FAP 2018 (Fundação de Amparo à Pesquisa da FCMSCSP) (Project “Autophagy and mitochondrial degradation modulation by lysine deacetylases in different cellular models of Amyotrophic Lateral Sclerosis”)

 

2015 - Today (FCMSCSP, São Paulo, Brazil) - Perspective of epigenetic therapy to Amyotrophic Lateral Sclerosis and Schizophrenia.

 

  • Financial Support - Grant Approved FAP 2019 (Project "Mitochondrial dysfunction evaluation in rats submitted to intrauterine hypoxia: studies in a pharmacological animal model of pre-eclapsia")

  • Financial Support - Grant Approved FAP 2017 (Fundação de Amparo à Pesquisa da FCMSCSP) (Project "Functional studies in lymphoblasts from Amyotrophic Lateral Sclerosis patients")

  • Financial Support - Grant Approved by JP FAPESP (Project: “The role of lysine(K)-deacetylases on mitochondrial disorders’s neuroprotection: Perspectives of epigenetic therapy for Amyotrophic Lateral Sclerosis and Schizophrenia”)

  • Financial Support - Grant Approved FAP 2016 (Fundação de Amparo à Pesquisa da FCMSCSP) (Project “The role of lysine(K)-deacetylases and mitochondrial dysfunction in different models of Schizophrenia”)

 

2008-2015 (CNC, Coimbra, Portugal) - Mitochondrial dysfunction and neuroprotection in Huntington’s disease models.

 

  • Financial Support - Grant Approved by FCT (Project “Role of sirtuin 3 on mitochondrial function and deacetylation of mitochondrial targets: relevance for Huntington’s disease”)

  • Post-Doc fellowship 1 - Approved by FCT: Project "Analysis of transcription deregulation in striatal neurons expressing normal and full-length mutant huntingtin: influence of histone deacetylase inhibitors and resveratrol"

  • Post-Doc fellowship 2- Approved by FCT: Project "Analysis of transcription deregulation in brain and peripheral Huntington’s disease models - influence of modulating histone deacetylases"

  • Other projects - Approved by FCT: Project "The role of histone deacetylases in mutant huntingtin acetylation and degradation and Neuroprotection induced by Insulin and IGF-1 in diabetes associated to Huntington’s Disease"

 

2012 (MIT, USA) - Fellowship  Approved by FCT: “Evaluation of transcription factors bymodification in RNA transcriptsthrough RNA-seqand CHIP-seq" - Lab Prof. Ernest Fraenkel:

 

2001-2008 (São Paulo, Brazil) - Mitochondrial dysfunction and its role to Huntington's disease.

 

  • PhD Project - Fellowship Approved by CAPES (Project "Study of cellular and molecular mechanisms related to the neurodegenerative process of Huntington’s disease")

  • PhD Intership (Rome, Italy) - Fellowship Approved by CAPES (Project "Study of calcium changes and autophagy during Huntington’s Disease")

  • Master Project - Fellowship Approved by FAPESP (Project “Study of cell death signalling and behavioural alterations in animal models of Huntington’s disease”)


To check the Research Groups from FCMSCSP, please, click  in the link below: