Research Areas
2017 - Today (FCMSCSP, São Paulo, Brazil) - Neurogenesis and Psychiatric disorders
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Financial Support - Grant Approved by SPRINT-FAPESP (Project "Mitochondrial metabolism and its relationship with neurogenesis in an anumal model of Schizophrenia with aging" intitulado “Age-related mitochondrial metabolism and its relationship with neurogenesis in an animal model of Schizophrenia”
2017 - Today (FCMSCSP, São Paulo, Brazil) - Autophay and Metabolism in Amyotrophic Lateral Sclerosis.
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Brazil Visiting Fellow – University of Birmingham, UK 2018 - “Autophagy investigatoin in iPSCs-derived neurons from different neurodegenerative models"
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Brazil Visiting Fellow – University of Birmingham, UK 2017 - “Autophagy pathways evaluations as a therapeutic strategy for rare and more prevalent neurodegenerative disorders"
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Financial Support - Grant Approved by FAPESP International Cooperation FAPESP-UoBirmingham-UoNottigham (Project: “Investigating cellular homeostatic mechanisms underlying rare and prevalent neurodegenerative diseases using human induced pluripotent stem cells”
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Financial Support - Grant Approved FAP 2018 (Fundação de Amparo à Pesquisa da FCMSCSP) (Project “Autophagy and mitochondrial degradation modulation by lysine deacetylases in different cellular models of Amyotrophic Lateral Sclerosis”)
2015 - Today (FCMSCSP, São Paulo, Brazil) - Perspective of epigenetic therapy to Amyotrophic Lateral Sclerosis and Schizophrenia.
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Financial Support - Grant Approved FAP 2019 (Project "Mitochondrial dysfunction evaluation in rats submitted to intrauterine hypoxia: studies in a pharmacological animal model of pre-eclapsia")
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Financial Support - Grant Approved FAP 2017 (Fundação de Amparo à Pesquisa da FCMSCSP) (Project "Functional studies in lymphoblasts from Amyotrophic Lateral Sclerosis patients")
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Financial Support - Grant Approved by JP FAPESP (Project: “The role of lysine(K)-deacetylases on mitochondrial disorders’s neuroprotection: Perspectives of epigenetic therapy for Amyotrophic Lateral Sclerosis and Schizophrenia”)
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Financial Support - Grant Approved FAP 2016 (Fundação de Amparo à Pesquisa da FCMSCSP) (Project “The role of lysine(K)-deacetylases and mitochondrial dysfunction in different models of Schizophrenia”)
2008-2015 (CNC, Coimbra, Portugal) - Mitochondrial dysfunction and neuroprotection in Huntington’s disease models.
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Financial Support - Grant Approved by FCT (Project “Role of sirtuin 3 on mitochondrial function and deacetylation of mitochondrial targets: relevance for Huntington’s disease”)
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Post-Doc fellowship 1 - Approved by FCT: Project "Analysis of transcription deregulation in striatal neurons expressing normal and full-length mutant huntingtin: influence of histone deacetylase inhibitors and resveratrol"
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Post-Doc fellowship 2- Approved by FCT: Project "Analysis of transcription deregulation in brain and peripheral Huntington’s disease models - influence of modulating histone deacetylases"
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Other projects - Approved by FCT: Project "The role of histone deacetylases in mutant huntingtin acetylation and degradation and Neuroprotection induced by Insulin and IGF-1 in diabetes associated to Huntington’s Disease"
2012 (MIT, USA) - Fellowship Approved by FCT: “Evaluation of transcription factors bymodification in RNA transcriptsthrough RNA-seqand CHIP-seq" - Lab Prof. Ernest Fraenkel:
2001-2008 (São Paulo, Brazil) - Mitochondrial dysfunction and its role to Huntington's disease.
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PhD Project - Fellowship Approved by CAPES (Project "Study of cellular and molecular mechanisms related to the neurodegenerative process of Huntington’s disease")
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PhD Intership (Rome, Italy) - Fellowship Approved by CAPES (Project "Study of calcium changes and autophagy during Huntington’s Disease")
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Master Project - Fellowship Approved by FAPESP (Project “Study of cell death signalling and behavioural alterations in animal models of Huntington’s disease”)